Scores
| Date | Opponent | Result | Attendance | Location |
|---|---|---|---|---|
| Fri, October 3 |
W
SF
26
-
23
LAR
|
73,652 | TD Garden | |
| Sun, September 28 |
L
SF
21
-
26
JAX
|
70,495 | American Airlines Center | |
| Sun, September 21 |
W
SF
16
-
15
ARI
|
70,414 | American Airlines Center | |
| Sun, September 14 |
W
SF
26
-
21
NO
|
70,078 | State Farm Arena | |
| Sun, September 7 |
W
SF
17
-
13
SEA
|
68,752 | American Airlines Center | |
| Sun, August 24 |
W
SF
30
-
23
LAC
|
71,124 | American Airlines Center | |
| Sat, August 16 |
W
SF
22
-
19
LV
|
62,027 | Bridgestone Arena | |
| Sun, August 10 |
L
SF
9
-
30
DEN
|
71,124 | American Airlines Center |